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$ Value

$521

Shares

41

Price

$13

Filed

Jun 27

Insider

Name

EcoR1 Capital, LLC

Title

CIK

0001587114

Roles

Director 10% Owner

Transaction Details

Transaction Date

2025-06-26

Code

F

Table

Non-Derivative

Ownership

Indirect

Equity Swap

No

Shares After

22,970,388

Footnotes

The reporting persons are EcoR1 Capital, LLC ("EcoR1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Funds"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein. | Qualified Fund acquired 4,818,424 shares of Common Stock in connection with the exercise of the pre-funded warrants. | After the transactions reported herein, Qualified Fund held 21,582,563 shares of the Issuer's Common Stock. | On June 26, 2025,the reporting persons exercised pre-funded warrants to purchase 5,086,521 shares of the Issuer's Common Stock for $0.0001 per share. The reporting persons paid the exercise price on a cashless basis, resulting in the Issuer withholding 41 of the warrant shares (including 38 warrant shares issuable to Qualified Fund) to pay the exercise price and issuing to the reporting persons the remaining 5,086,480 shares. | Qualified Fund exercised 4,818,462 of the pre-funded warrants reported in this transaction. | The pre-funded warrants did not have an expiration date.

Filing Info

Accession No.

0000935836-25-000438

Form Type

4

Issuer CIK

0001937653

EcoR1 Capital, LLC's History

Date Ticker Type Value
2026-04-20 TRAX $65.0M
2025-07-30 ADAP $2.8M
2025-07-29 ADAP $272K
2025-07-28 ADAP $3.8M
2025-06-26 ZYME X $509
2025-06-26 ZYME F $521
2025-06-26 ZYME X $0
2025-05-19 ZYME $70K
2025-05-15 ITOS $26.4M
2025-05-15 ZYME $566K

Other Insiders at ZYME (90d)

Insider Bought Sold Last
Platshon Scott
EVP, Chief Business Officer
2026-04-09
Stafford Kristin
EVP, Chief Financial Officer
2026-04-06
Schayowitz Adam
See Remarks
2026-04-09