Transaction Details

Footnotes

All transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan established by Mr. Talwalkar on May 12, 2025. | Represents the weighted-average sale price per share of a series of transactions, all of which were executed on February 23, 2026. The actual sale prices ranged from a low of $145.190 to a high of $145.530, inclusive. Mr. Talwalkar undertakes to provide upon request of the SEC staff, iRhythm Holdings, Inc. or any security holder of iRhythm Holdings, Inc., full information regarding the numbers of shares sold at each price within the range. The weighted-average sale price reflected has been rounded to 3 decimal points. | Represents the weighted-average sale price per share of a series of transactions, all of which were executed on February 23, 2026. The actual sale prices ranged from a low of $146.300 to a high of $147.200, inclusive. Mr. Talwalkar undertakes to provide upon request of the SEC staff, iRhythm Holdings, Inc. or any security holder of iRhythm Holdings, Inc., full information regarding the numbers of shares sold at each price within the range. The weighted-average sale price reflected has been rounded to 3 decimal points. | Represents the weighted-average sale price per share of a series of transactions, all of which were executed on February 23, 2026. The actual sale prices ranged from a low of $147.340 to a high of $148.130, inclusive. Mr. Talwalkar undertakes to provide upon request of the SEC staff, iRhythm Holdings, Inc. or any security holder of iRhythm Holdings, Inc., full information regarding the numbers of shares sold at each price within the range. The weighted-average sale price reflected has been rounded to 3 decimal points. | The option, originally granted on May 23, 2016 for 21,248 shares, vested in thirty-six equal monthly installments. This option has an expiration date of May 23, 2026. The Rule 10b5-1 trading plan of Mr. Talwalkar solely covers shares subject to options expiring in 2026 and 2027.