Transaction Details

Footnotes

The shares are held directly by BKB Growth Investments, LLC ("BKB"). The Reporting Person is a co-manager of Tiger Lily Capital, LLC, the manager of BKB, and has shared voting and investment power with respect to the shares held by BKB. | The change in the total shares held prior to the transactions reported herein reflects a change in form of ownership and, therefore, was not required to be reported pursuant to Section 16. | The shares are held directly by The Paul B. Manning Revocable Trust dated May 10, 2000 (the "Revocable Trust"). The Reporting Person is the trustee of the Revocable Trust and has sole voting and investment power with respect to the shares held by the Revocable Trust. | The shares are held directly by BKB G2 Investments, LLC ("BKB G2"). The Reporting Person is a co-manager of Tiger Lily Capital, LLC, the manager of BKB G2, and has shared voting and investment power with respect to the shares held by BKB G2. | The shares are held directly by The PBM 2023 Grantor Retained Annuity Trust (the "2023 Annuity Trust"). The Reporting Person is the trustee of the 2023 Annuity Trust and has sole voting and investment power with respect to the shares held by the 2023 Annuity Trust. | The shares are held directly by The PBM 2025 Grantor Retained Annuity Trust (the "2025 Annuity Trust"). The Reporting Person is the trustee of the 2025 Annuity Trust and has sole voting and investment power with respect to the shares held by the 2025 Annuity Trust.