Transaction Details

Footnotes

These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 4, 2025. | The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $102.52 to $103.51, inclusive. The reporting person undertakes to provide to the staff of the Securities and Exchange Commission, Nuvalent, Inc. or any security holder of Nuvalent, Inc., upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) through (4) of this Form 4. | The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $103.52 to $104.51, inclusive. | The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $104.52 to $105.48, inclusive. | The shares underlying this option are fully vested. | The shares underlying this option have vested or shall vest over the four years following January 6, 2023 in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date.