Transaction Details

Footnotes

Represents the issuance of Restricted Stock Units ("RSUs") to the Reporting Person in lieu of quarterly retainer fees of $20,625 for service on the Issuer's Board of Directors. The RSUs were fully vested at the time of issuance. | Each RSU represents a contingent right to receive one share of the Issuer's Common Stock. | The Reporting Person is a managing member of Sofinnova Management IX, L.L.C. ("Sofinnova Management IX"). Sofinnova Management IX is the general partner of Sofinnova Venture Partners IX, L.P . The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.